| 发明名称 |
Methods of modulating immune coagulation |
| 摘要 |
<p>Methods for mediating immune coagulation using novel antibodies and compounds are described. A protein Fgl2 having direct prothrombinase activity has been identified. Inhibitors of Fgl2 are useful in preventing and treating diseases which require a reduction in immune coagulation including bacterial and viral infections, allograft and xenograft rejection, glomerulonephritis, cancer, a number of gastrointestinal diseases and fetal loss.</p> |
| 申请公布号 |
AU742076(B2) |
申请公布日期 |
2001.12.13 |
| 申请号 |
AU19980074213 |
申请日期 |
1998.05.15 |
| 申请人 |
TRANSPLANTATION TECHNOLOGIES INC |
发明人 |
GARY LEVY;DAVID A. CLARK |
| 分类号 |
A61K45/00;A61K31/7088;A61K38/00;A61K39/00;A61K39/395;A61K48/00;A61P1/00;A61P7/02;A61P13/12;A61P31/04;A61P31/12;A61P35/00;A61P37/06;A61P43/00;C07K16/40;C12N9/64;C12N15/55;G01N33/68;G01N33/86;(IPC1-7):A61K39/00;A61K31/70;C12Q1/68;G01N33/573 |
主分类号 |
A61K45/00 |
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