发明名称 |
STABLE ISOTOPE LABELING OF PACLITAXEL |
摘要 |
The present invention relates to isotopically labeled analogs of taxane molecules, which are synthetically formed to have incorporated therein at a selected position a stable isotope of an element existing at the selected position in the standard taxane molecule. The present invention also relates to methods of producing isotopically labeled taxane molecules, and methods of determining the retention of a target taxane in a biological material derived from an organism that has been dosed with the target taxane.
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申请公布号 |
WO0194328(A1) |
申请公布日期 |
2001.12.13 |
申请号 |
WO2001US40876 |
申请日期 |
2001.06.07 |
申请人 |
NAPRO BIOTHERAPEUTICS, INC. |
发明人 |
ALEXANDER, MICHAEL, S.;MCCHESNEY, JAMES, D.;ZYGMUNT, JAN |
分类号 |
G01N33/483;C07D305/14;G01N33/60;(IPC1-7):C07D305/14;A61K31/335 |
主分类号 |
G01N33/483 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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