摘要 |
In nuclear magnetic resonance imaging of the human brain or the like, multiple quantum coherences, such as intermolecular double quantum coherence (iDQC) between water molecules, are used for soft tissue contrast. A group of pulse sequences are used in which, (a) The standard beta=pi/2 pulse in the original CRAZED sequence is replaced with a pi/3 pulse. The maximum signal derived from iDQCs is increased by a factor of 3{square root}{square root over (3)}/4. (b) The position of the acquisition window is adjusted, and a large acquisition window (small bandwidth) is used to sample a broad range of time-domain signals. (c) Receiver dynamic range is optimized. (d) A two-step phase cycle scheme for iDQC-encode gradients is designed to remove additional undesired coherence pathways.
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