SCREENING-METHOD FOR MODULATORS OF METHYLTRANSFERASE-DEPENDENT CHROMOSOME STABILITY
摘要
A method for identifying compounds that alter higher order chromatin dependent chromosome stability is based on determining the compounds' ability to modify a methyltransferase with Suv39h-like methyltransferase activity. The identified compounds are useful in therapy, in particular the therapy of human cancer and for contraception.
申请公布号
WO0194620(A1)
申请公布日期
2001.12.13
申请号
WO2001EP06485
申请日期
2001.06.07
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;JENUWEIN, THOMAS;REA, STEPHEN;EISENHABER, FRANK;O'CARROLL, DONAL
