SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS

摘要

The present invention relates to chemical compounds, pharmaceutical compositions comprising said compounds, methods of treatment administering these compounds to mammalian hosts, and processes for their preparation. Specifically, the invention relates to a means to enhance insulin-dependent glucose uptake. More specifically, the invention concerns compounds and pharmaceutical compositions that activate the insulin receptor kinase, which leads to increased sensitivity to insulin and an increase in glucose uptake, as well as processes for the preparation of the compounds. The invention als o specifically concerns methods for treating humans with hyperglycemia, especially for the treatment of Type II diabetes.