<p>Nucleozymes comprising non-nucleotide spacer molecules have catalytic activity are more resistant to degradation than all RNA ribozymes and may further comprise deoxyribonucleotides and/or nucleic acid analogues. <IMAGE> <IMAGE></p>
申请公布号
EP1162263(A1)
申请公布日期
2001.12.12
申请号
EP20010202774
申请日期
1993.01.28
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人
USMAN, NASSIM;PEREAULT, JEAN-PIERRE;RICH, ALEXANDER;CEDERGREN, ROBERT J.;YANG, JING-HUA
