| 发明名称 |
Substituted pyrazoles functioning as p38 kinase inhibitors |
| 摘要 |
<p>A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula (IA), <CHEM> wherein R<1>, R<2>, R<3> and R<4> are as described in the specification.</p> |
| 申请公布号 |
CZ20011714(A3) |
申请公布日期 |
2001.12.12 |
| 申请号 |
CZ20010001714 |
申请日期 |
1999.11.17 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
ANANTANARAYAN ASHOK;CLARE MICHAEL;COLLINS PAUL W.;CRICH JOYCE Z.;DEVRAJ RAJESH;FLYNN DANIEL L.;GENG LIFENG;GRANETO MATTHEW J.;HANSON GUNNAR J.;HARTMANN SUSAN J.;HEPPERLE MICHAEL;HUANG HE;KHANNA ISH K.;KOSZYK FRANCIS J.;LIAO SHUYUAN;METZ SUZANNE;PARTIS RICHARD A.;PERRY THAO D.;RAO SHASHIDHAR N.;SELNESS SHAUN RAJ;SOUTH MICHAEL S.;STEALEY MICHAEL A.;STEALEY MICHAEL A.;TALLEY JOHN JEFFREY;VAZQUEZ MICHAEL L.;WEIER RICHARD M.;YU YIANGDONG;YU YI;HANAU CATHLEEN E. |
| 分类号 |
A61K31/415;A61K31/44;A61K31/4439;A61K31/445;A61K31/454;A61K31/47;A61K31/496;A61K31/50;A61K31/505;A61K31/506;A61K31/52;A61K31/5377;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P19/00;A61P19/02;A61P19/06;A61P29/00;A61P29/02;A61P43/00;C07D401/04;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D453/02;C07D471/04;C07D473/00;C07D487/04;(IPC1-7):C07D401/04 |
主分类号 |
A61K31/415 |
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