Means for maintenance and/or correction of glucose concentration in blood

摘要

The invention relates to preparations that are useful in maintaining mammalian blood glucose concentrations. These preparations contain insulin, and a polymeric matrix. The polymeric matrix has a core of biodegradable, hydrophobic polymer, and an outer shell of a biodegradable, hydrophobic polymer. Alternately, the formulations contain insulin, a polymeric matrix, and a histone.