| 摘要 |
The polypeptides of the present invention are produced and secreted in pro-B cells and may be used for diseases relating to undergrown or abnormal proliferation of hematopoietic cells, neuronal enhancement or depression, immunological enhancement and depression, for example, inflammatory diseases (rheumatoid arthritis, ulcerative colitis, etc.), hematopoietic stemcytopenia after bone marrow transplantation, leukocytopenia, thrombocytopenia, B lymphopenia and T lymphopenia after chemotherapy, anemia, infectious diseases, cancer, leukocytosis, AIDS, neurodegenerative diseases (Alzheimer, multiple sclerosis, etc.), prevention or treatment of neuronal injury, prevention or treatment of disorder of bone metabolism (osteoporosis , etc.) or tissue repair. The DNA of the present invention may be utilized as an important and essential template in preparing the polypeptides of the presen t invention which are expected to be useful for diagnosis and treatment of gen e diseases.
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