Immobilized nucleic acids and uses thereof

摘要

One aspect of the present invention relates to an immobilized nucleic acid comprising a nucleic acid and a matrix where the nucleic acid is a Spiegelmer and the Spiegelmer is functionally active. Another aspect of the invention concerns an immobilized nucleic acid comprising a nucleic acid and a matrix where the nucleic acid is coupled to the matrix at least via its 3' end and the nucleic acid is a functional nucleic acid. Finally a further aspect of the invention concerns the use of such immobilized nucleic acids as affinity ligands for example in chromatography and in apheresis.