SUBSTITUTED INDANYLIDINE ACETYL GUANIDINES, METHOD OF PREPARING THEREOF, USE OF MEDICINAL OR DIAGNOSTIC AGENTS AND MEDICAL AGENTS COMPRISING SAID COMPOUNDS

摘要

medicine. SUBSTANCE: described are substituted, indanylidine acetyl guanidines of formula I: wherein R1,R2,R3,R4,R5,R6 are hydrogen, alkyl, alkyloxy, F,Cl, Br,F: R7,R9,R9,R10 are hydrogen, and X is O. Compound of general formula I have inhibiting activity with respect to Na/H exchange and are therefore used as medicinals or diagnostic agents. Described is method of formula I by reacting compound of formula V: wherein Y is alkoxy, halogen or imidazolyl with guandine of formula VI . EFFECT: improved properties of the title compounds. 16 cl, 2 tbl