| 发明名称 |
METHOD FOR IDENTIFYING COMPOUNDS FOR MODULATING THE ACTIVITY OF A TUMOUR SUPPRESSOR PROTEIN |
| 摘要 |
The invention relates to a method for identifying compounds which alter the activity of the intracellular tumour suppressor gene <i>nf2</i>, whereby the activity of the protein NF2 that is coded by the gene <i>nf2</i> is altered by means of the extra-cellular interaction of the compounds with the cell surface protein CD44. |
| 申请公布号 |
WO0192876(A2) |
申请公布日期 |
2001.12.06 |
| 申请号 |
WO2001EP05842 |
申请日期 |
2001.05.22 |
| 申请人 |
FORSCHUNGSZENTRUM KARLSRUHE GMBH;MORRISON, HELEN;PONTA, HELMUT;HERRLICH, PETER |
发明人 |
MORRISON, HELEN;PONTA, HELMUT;HERRLICH, PETER |
| 分类号 |
A61K39/395;A61K45/00;A61P35/00;C07K16/28;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/574 |
主分类号 |
A61K39/395 |
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