发明名称 NUCLEIC ACID MOLECULE COMPRISING A NUCLEIC ACID SEQUENCE CODING FOR AN SDF-1 GAMMA CHEMOKINE, A NEUROPEPTIDE PRECURSOR OR AT LEAST ONE NEUROPEPTIDE
摘要 The invention relates to a nucleic acid molecule comprising a nucleic acid sequence coding for a chemokine, a neuropeptide precursor or at least one neuropeptide, in addition to host cells containing said nucleic acid molecule. The invention also relates to a polypeptide molecule which acts as a chemokine or a neuropeptide or contains at least one neuropeptide, and to fragments thereof containing at least one neuropeptide . The invention further relates to a method for producing a polypeptide molecule or a fragment thereof. Also disclosed are antibodies, detection methods, test kits and pharmaceutical compositions. The aim of the invention is to provide novel agents which can be used specifically to diagnose and/or treat diseases which are linked to a defect in the SDF-1 factor or one of the receptors (CXCR4) thereof.
申请公布号 WO0192530(A1) 申请公布日期 2001.12.06
申请号 WO2001EP06250 申请日期 2001.06.01
申请人 RHEIN BIOTECH GESELLSCHAFT FUER NEUE BIOTECHNOLOGISCHE PROZESSE UND PRODUKTE MBH;MUELLER, HANS, WERNER;BOSSE, FRANK;GLEICHMANN, MARC;GILLEN, CLEMENS;AUER, JOHANNES 发明人 MUELLER, HANS, WERNER;BOSSE, FRANK;GLEICHMANN, MARC;GILLEN, CLEMENS;AUER, JOHANNES
分类号 G01N33/53;A61K38/00;A61K39/395;A61K48/00;A61P7/00;A61P9/00;A61P25/00;A61P25/28;A61P31/18;A61P37/00;C07K14/52;C07K16/24;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/19;C12P21/02;C12Q1/68;C12R1/645;C12R1/865;G01N33/566 主分类号 G01N33/53
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