发明名称 METHOD OF IDENTIFYING AND/OR ISOLATING STEM CELLS AND PROGNOSING RESPONSIVENESS TO LEUKEMIA TREATMENT
摘要 The present invention includes methods of identifying and/or isolating stem cells based on expression of BCRP. The present invention also describes methods of obtaining and/or using cell populations enriched for stem cells. In addition, methods are provided for diagnosing and/or prognosing leukemia, particularly human acute myelogenous leukemia (AML), through assaying for BCRP expression in leukemic cells.
申请公布号 WO0192877(A2) 申请公布日期 2001.12.06
申请号 WO2001US17459 申请日期 2001.05.30
申请人 ST. JUDE CHILDREN'S RESEARCH HOSPITAL;SORRENTINO, BRIAN;SCHUETZ, JOHN 发明人 SORRENTINO, BRIAN;SCHUETZ, JOHN
分类号 G01N33/48;A61K35/12;A61K48/00;C07K14/705;C07K16/18;C12N5/06;C12N15/09;C12Q1/02;C12Q1/68;G01N33/50;G01N33/53;G01N33/555;G01N33/569;G01N33/574 主分类号 G01N33/48
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