发明名称 |
METHOD OF IDENTIFYING AND/OR ISOLATING STEM CELLS AND PROGNOSING RESPONSIVENESS TO LEUKEMIA TREATMENT |
摘要 |
The present invention includes methods of identifying and/or isolating stem cells based on expression of BCRP. The present invention also describes methods of obtaining and/or using cell populations enriched for stem cells. In addition, methods are provided for diagnosing and/or prognosing leukemia, particularly human acute myelogenous leukemia (AML), through assaying for BCRP expression in leukemic cells. |
申请公布号 |
WO0192877(A2) |
申请公布日期 |
2001.12.06 |
申请号 |
WO2001US17459 |
申请日期 |
2001.05.30 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL;SORRENTINO, BRIAN;SCHUETZ, JOHN |
发明人 |
SORRENTINO, BRIAN;SCHUETZ, JOHN |
分类号 |
G01N33/48;A61K35/12;A61K48/00;C07K14/705;C07K16/18;C12N5/06;C12N15/09;C12Q1/02;C12Q1/68;G01N33/50;G01N33/53;G01N33/555;G01N33/569;G01N33/574 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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