POLYMORPHISMS ASSOCIATED WITH INSULIN-SIGNALING AND GLUCOSE-TRANSPORT PATHWAYS

摘要

The invention discloses a collection of polymorphic sites in genes known or suspected to have a role in metabolic diseases including diabetes, obesity, cardiovascular disorders, hypertension and some forms of cancers that may share the same signaling pathways indicated in this application. The invention provides nucleic acids including such polymorphic sites. The nucleic acids can be used as probes or primers or for expressing variant proteins. The invention also provide methods of analyzing the polymorphic forms occupying the polymorphic sites.