发明名称 |
SUBSTANCES WK-5344A AND WK-5344B AND PROCESS FOR PRODUCING THE SAME |
摘要 |
<p>The present invention relates to novel substance having inhibitory action on cholesteryl ester transfer protein, WK-5344A substance and WK-5344B substance, and process for production thereof. A microorganism belonging to genus Streptomyces having ability to produce WK-5344A substance and WK-5344B substance is cultured in a medium, and the WK-5344A substance and the WK-5344B substance are accumulated in the medium, then the WK-5344A substance and the WK-5344B substance are isolated from the said medium. Since the present substance shows significant inhibitory action on cholesteryl ester transfer protein, the substance is effective for prevention and treatment of diseases caused by accumulation of cholesterol in human.</p> |
申请公布号 |
EP1160330(A1) |
申请公布日期 |
2001.12.05 |
申请号 |
EP19990973760 |
申请日期 |
1999.03.08 |
申请人 |
THE KITASATO INSTITUTE |
发明人 |
OMURA, SATOSHI;TOMODA, HIROSHI;TAKAHASHI, YOKO |
分类号 |
C07F15/02;C12N1/20;C12P9/00;C12P13/00;C12R1/465;(IPC1-7):C12P13/00 |
主分类号 |
C07F15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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