Formulations for use in enzyme-orthokeratology

摘要

Compositions, methods and apparatus for correcting refractive errors of the eye are disclosed. Accelerated reshaping of the corneal tissue is accomplished by administering enzyme or enzyme inhibitory agents to the eye. After temporarily softening the cornea a rigid contact lens having a concave curvature is fitted. This corrects a refractive error. A softened cornea rapidly reshapes its convex curvature to the concave curvature of the contact lens or series of lenses, thereby rendering the eye emmetropic. Enzymes and/or other agents dissipate from the cornea, and the cornea "hardens" to retain the new emmetropic shape. After "hardening" has occurred, the lens rendering the eye emmetropic is removed. <IMAGE>