发明名称 |
Method of identifying compounds having antiepileptic anticonvulsant or anxiolytic activities |
摘要 |
The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.
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申请公布号 |
US6326156(B1) |
申请公布日期 |
2001.12.04 |
申请号 |
US19970868355 |
申请日期 |
1997.06.03 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
CIVELLI OLIVIER;MARTIN JAMES RICHARD;MONSMA FREDERICK;MOREAU JEAN-LUC;NOTHACKER HANS-PETER;REINSCHEID RAINER |
分类号 |
G01N33/53;A61K38/00;A61K38/10;A61P25/08;A61P25/20;A61P25/26;G01N33/15;G01N33/566;G01N33/94;(IPC1-7):G01N33/53;G01N33/567 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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