发明名称 |
Determination of naaladase inhibitors |
摘要 |
The invention relates to a method for determining inhibitors of the enzyme N-acetyl-alpha-linked acidic dipeptidase (NAALADase). According to said method, the enzymatic transformation of a substrate that is radioactively marked on the C-terminal glutamate radical is determined by its bonding to fluo beads. The invention also relates to novel enzyme substrates and to their use in said method. |
申请公布号 |
AU6032001(A) |
申请公布日期 |
2001.12.03 |
申请号 |
AU20010060320 |
申请日期 |
2001.05.19 |
申请人 |
BOEHRINGER INGELHEIM PHARMA KG |
发明人 |
RUTH JOSTOCK;ADRIAN CARTER;EDWARD LEON BARSOUMIAN;MATTHIAS GRAUERT;STEFAN PETERS |
分类号 |
A61K38/00;C07K5/072;C12Q1/37;G01N33/542;G01N33/573;G01N33/60 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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