发明名称 |
NOVEL BENZIMIDAZOLE DERIVATIVES HAVING CGMP-PHOSPHODISTERASE INHIBITING ACTIVITY |
摘要 |
<p>PCT No. PCT/JP96/01841 Sec. 371 Date Mar. 6, 1997 Sec. 102(e) Date Mar. 6, 1997 PCT Filed Jul. 3, 1996 PCT Pub. No. WO97/03070 PCT Pub. Date Jan. 30, 1997The present invention provides novel benzimidazole derivatives or salts thereof represented by the general formula, wherein R1 is a hydrogen atom or a halogen atom; R2 is a phenyl-lower alkyl group; R3 is a heterocyclic group selected from the group consisting of an indolyl group, indolinyl group, 1H-indazolyl group, 2(1H)-quinolinonyl group, 3,4-dihydro-2(1H)-quinolinonyl group and 1,4-benzoxazinyl group; A is a lower alkylene group; n is 0 or 1. The benzimidazole derivatives or salts of the present invention are effective agents for treating various arteriosclerotic diseases.</p> |
申请公布号 |
GR3036420(T3) |
申请公布日期 |
2001.11.30 |
申请号 |
GR20010401271T |
申请日期 |
2001.08.20 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
NISHI, TAKAO;SATO, SEIJI;NAGATANI, TAKESHI;YUKAWA, HIROTAKA;KOGA, NOBUYUKI;SAITO, MASAHIRO;YOSHINAGA, SHINJI |
分类号 |
C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D413/12;C07D413/14;C07D521/00;(IPC1-7):C07D403/12;A61K31/415;C07D405/14 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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