Celleadhesjons-inhiberende antiinflammasjon og immun- suppressive forbindelser
摘要
The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal. <CHEM>
申请公布号
NO20014767(A)
申请公布日期
2001.11.30
申请号
NO20010004767
申请日期
2001.10.01
申请人
ICOS CORP
发明人
LIU, GANG;PEI, ZHONGHUA;GELDERN, THOMAS W. VON;WINN, MARTIN;XIN, ZHILI;WANG, SHELDON;ZHU, GUI-DONG;FREEMAN, JENNIFER C;GUNAWARDANA, INDRANI W;STAEGER, MICHAEL A;JAE, HWAN-SOO;LYNCH, JOHN K.
