| 摘要 |
Described is a method of treating inflammation or inflammatory disease, bacterial infection, arthritis and stroke in an animal or mammal, which comprises the steps of administering an effective amount of a pADPRT inhibitory compound. The pADPRT inhibitory compound is selected from the group consisting of formulas (I), (II), (III) wherein, R1, R2, R3, R4, R5 and R6 are each selected from the group consisting of hydrogen, hydroxy, amino, alkyl, alkoxy, cycloalkyl or phenol, optionally substituted with alkyl, alkoxy, hydroxy or halo, and only one of R1, R2, R3, R4, R5 and R6 is amino in the manufacture of a medicament for treating inflammation or inflammatory diseases.
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