发明名称 |
METHOD FOR PRODUCING 2-CHLORO-5-CHLOROMETHYL-1,3-THIAZOLE |
摘要 |
The invention relates to a method for producing 2-chloro-5-chloromethyl-1,3-thiazole. According to said method, allyl isothiocyanate of formula CH2=CH-CH2-NCS is reacted with 1 to 2 mol of a chlorinating agent per mol allyl isothiocyanate at - 40 DEG C to + 30 DEG C in a solvent that is inert in the reaction conditions. 1 to 5 mol oxidizing agent per mol allyl isothiocyanate is added to the resulting reaction mixture at a reaction temperature of 0 DEG C to the boiling temperature of the solvent used and 2-chloro-5-chloromethyl-1,3-thiazole is isolated from the reaction mixture and optionally, converted into highly pure 2-chloro-5-chloromethyl-1,3-thiazole by crystallization.
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申请公布号 |
WO0190089(A1) |
申请公布日期 |
2001.11.29 |
申请号 |
WO2001EP04693 |
申请日期 |
2001.04.26 |
申请人 |
DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG;KRICH, SYLVIA;BURGER, CHRISTIAN;ALTREITER, JOHANN;ZWOELFER, BIRGIT |
发明人 |
KRICH, SYLVIA;BURGER, CHRISTIAN;ALTREITER, JOHANN;ZWOELFER, BIRGIT |
分类号 |
C07D277/20;C07D277/32;(IPC1-7):C07D277/32 |
主分类号 |
C07D277/20 |
代理机构 |
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