DERIVATIVES OF 2-AMINOTETRALINS AND PHARMACEUTICAL ANALOGS THEREOF EXHIBITING DIFFERENTIAL CNS RECEPTOR ACTIVITY AND BEHAVIOR

摘要

Aminotetralin derivatives and pharmacological analogs thereof which contain an N-propynyl group exhibit differential dopaminergenic receptor activity. The subject compounds are useful in affecting dopamine receptor activity, particularly in exhibiting differing activity among the various dopamine receptor subtypes. The compounds are useful in treating CNS disorders in mammals in general, and humans in particular.