摘要 |
The invention provides isolated nucleic acids molecules, designated 46638 nucleic acid molecules, which encode novel lipoxygenase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 46638 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 46638 gene has been introduced or disrupted. The invention still further provides isolated 46638 proteins, fusion proteins, antigenic peptides and anti-46638 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |