F-PROTEIN EPITOPE-BASED VACCINE FOR RESPIRATORY SYNCYTIAL VIRUS INFECTION

摘要

The present invention relates to a vaccine that comprises selected epitopes within the F protein structure that have been proven to specifically interact with known potent neutralizing antibodies while simultaneously being presented as part of a synthetic structure that offers these epitopes apart from the other non-neutralizing antigenic determinants of the virus but held in a native conformational form and thereby capable of eliciting neutralizing antibodies.