发明名称 |
TREATING A VARIETY OF PATHOLOGICAL CONDITIONS, INCLUDING SPASTICITY AND CONVULSIONS, BY EFFECTING MODULATION OF CNS ACTIVITY WITH ISOVALERAMIDE, ISOVALERIC ACID, OR A RELATED COMPOUND |
摘要 |
Preparations and extracts of valerian, as well as isovaleramide, isovaleric acid, and certain structurally related compounds exhibit clinically significant pharmacological properties which implicate a treatment for a variety of pathological conditions, including spasticity and convulsions, which are ameliorated by effecting a modulation of CNS activity. The compositions in question generally are non-cytotoxic and do not elicit weakness or sedative activity at doses that are effective for the symptomatic treatment of such pathological conditions.
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申请公布号 |
WO0051586(A3) |
申请公布日期 |
2001.11.29 |
申请号 |
WO2000US05324 |
申请日期 |
2000.03.01 |
申请人 |
NPS PHARMACEUTICALS, INC. |
发明人 |
ARTMAN, LINDA, D.;BALANDRIN, MANUEL;SMITH, ROBERT, L. |
分类号 |
A61K31/16;A61K31/167;A61K31/18;A61K31/19;A61K31/197;A61K31/198;A61K31/22;A61K31/222;A61K31/255;A61K31/27;A61K31/575;A61K31/60;A61K36/84;(IPC1-7):A61K31/19;A61K31/616;A61P25/00;A61P25/08;A61P25/14;A61P25/18;A61P25/24;A61P25/28;A61P25/30;A61P25/06 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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