The present invention provides polypeptides having pyrimidine glycosylase activity, preferably, pyrimidine glycosylase/AP lyase activity. The polypeptides include a targeting sequence, preferably an exogenous target sequence. The invention includes polynucleotides that include a coding sequence encoding the polypeptides of the present invention. Also provided by the invention are methods of using the polypeptides.
申请公布号
WO0190332(A2)
申请公布日期
2001.11.29
申请号
WO2001US16900
申请日期
2001.05.23
申请人
THE UNIVERSITY OF TEXAS SYSTEM;LLOYD, ROBERT, STEPHEN;MCCULLOUGH, AMANDA, K.;NGUYEN, KHOA