发明名称 POLYMORPHIC CRYSTALLINE FORMS OF 1-PYRROLE DERIVATIVES
摘要 The invention relates to new crystalline forms I and II of (4R-cis)-6-[2-[3-phenyl-4-(phenyl-carbamoyl)-2-(4-fluoro-phenyl)-5-(1- methyl-ethyl)-pyrrol-1-yl]-ethyl]-2,2-dimethyl-[1,3]dioxane-4-yl-acetic acid-tertiary butyl ester of the Formula (I) and a process for the preparation thereof. The new polymorphs of the present invention are useful pharmaceutical intermediates which can be used in the preparation of the hydroxymethyl-glutaryl coenzyme (HMG-COA) reducing enzyme inhibitor having the INN (International Non-proprietory Name) atorvastatin
申请公布号 HU0103702(D0) 申请公布日期 2001.11.28
申请号 HU20010003702 申请日期 2001.09.14
申请人 EGIS GYOGYSZERGYAR RT. 发明人 DR. BARKOCZY JOZSEF;DR. GREFF ZOLTAN;DR. KOTAY NAGY PETER;DR. SIMIG GYULA;BARTHA FERENC;DR. NAGY KALMAN;DR. VERECZKEYNE DONATH GYOERGYI;SZENT KIRALYI ZSUZSA
分类号 C07D405/06 主分类号 C07D405/06
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