发明名称 |
PRRSV REPLICON |
摘要 |
The invention relates to the field of PRRS viruses and infectious clones obtained from PRRS viruses. Furthermore, the invention relates to vaccines and diagnostic assays obtainable by using and modifying such infectious clones of PRRS viruses. The invention provides a porcine reproductive and respiratory syndrome virus (PRRSV) replicon having at least some of its original PRRSV nucleic acid deleted, said replicon capable of in vivo RNA replication, said replicon further having been deprived of at least some of its original PRRSV nucleic acid and/or having been supplemented with nucleic acid derived from a heterologous microorganism. |
申请公布号 |
EP1157121(A1) |
申请公布日期 |
2001.11.28 |
申请号 |
EP20000909797 |
申请日期 |
2000.03.08 |
申请人 |
STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK |
发明人 |
MEULENBERG, JANNEKE;VAN NIEUWSTADT, ANTONIE, PAUL;LANGEVELD, JAN;VERHEIJE, HELENE |
分类号 |
A61K39/00;A61K39/12;A61P31/12;C07K14/08;C12N7/01;C12N7/04;C12N15/40;C12N15/86;(IPC1-7):C12N15/86 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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