PHARMACEUTICAL CONTAINING CYANOPHENYL DERIVATIVE AS ACTIVE INGREDIENT

摘要

PROBLEM TO BE SOLVED: To obtain a pharmaceutical containing a cyanophenyl derivative as an active ingredient which exhibits antiandrogen activity and is useful in the prophylaxis or treatment for prostatic cancer, prostatic hypertrophy or the like. SOLUTION: This cyanophenyl derivative consists of a piperazino substituted new cyanophenyl derivative of which the substituted carbamoyl or substituted sulfamoyl group bearing an aryl or heterocyclic ring or the like that may have a substituent is combined with a nitrogen atom on a piperazine ring. This compound exhibits antiandrogen activity and is useful in the prophylaxis or treatment for prostatic cancer, prostatic hypertrophy or the like.