发明名称 |
Microcapillary-based flow-through immunosensor and displacement immunoassay using the same |
摘要 |
A displacement-type flow immunoassay is performed using a microcapillary passage. The inner wall of the microcapillary passage has immobilized thereon antibodies to the antigen of interest. Labeled antigen is immunologically bound to the immobilized antibodies. Sample antigen passing through the column displaces the labeled antigen. Downstream, the displaced labeled antigen is detected. The microcapillary format of the present invention enhances the sensitivity of the immunoassay over the sensitivity of displacement-type flow immunoassays performed in a column at similar flow rates.
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申请公布号 |
US6323042(B1) |
申请公布日期 |
2001.11.27 |
申请号 |
US19990435833 |
申请日期 |
1999.11.08 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY |
发明人 |
NARANG UPVAN;GAUGER PAUL R.;LIGLER FRANCES S. |
分类号 |
G01N33/543;(IPC1-7):G01N33/558 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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