发明名称 |
Vaccines, immunotherapeutics and methods for using the same |
摘要 |
Compositions comprising isolated RANTES protein and/or a nucleic acid molecule that encodes RANTES protein in combination with isolated IL-8 protein and/or a nucleic acid molecule that encodes IL-8 protein and optionally further comprising an immunogen and/or a nucleic acid molecule that encodes an immunogen are disclosed. Methods of inducing an immune response in an individual against an immunogen comprising administering to the individual isolated RANTES protein and/or a nucleic acid molecule that encodes RANTES protein in combination with isolated IL-8 protein and/or a nucleic acid molecule that encodes IL-8 protein and additionally a target protein and/or a nucleic acid molecule that encodes a target protein are disclosed. Methods of modulating an individual's immune system comprising administering to the individual isolated RANTES protein and/or a nucleic acid molecule that encodes RANTES protein in combination with isolated IL-8 protein and/or a nucleic acid molecule that encodes IL-8 protein are also disclosed. In addition, recombinant vaccines, live attenuated pathogens comprising a nucleotide sequence that encodes IL-8 and a nucleotide sequence that encodes RANTES and methods of the same are disclosed. |
申请公布号 |
AU6159001(A) |
申请公布日期 |
2001.11.26 |
申请号 |
AU20010061590 |
申请日期 |
2001.05.14 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
DAVID B. WEINER;JEONG-IM SIN |
分类号 |
C12N15/09;A61K38/19;A61K39/12;A61K39/245;A61K39/39;C12N7/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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