| 摘要 |
Thiophenamide compounds of the general formula (I) exhibiting a TNF- alpha production inhibiting effect, wherein R<1> to R<4> are each hydrogen, hydroxyl, allyl, optionally substituted lower alkyl, or optionally substituted aryl, or alternatively R<1> and R<2> or R<3> and R<4> may be united to form a ring, or R<1> and R<2> or R<3> and R<4> may together represent an oxygen atom; Ar<1> is optionally substituted nitrogenous heteroaryl; Ar<2> is optionally substituted aryl or optionally substituted cycloalkyl; m is an integer of 0 to 7; n and p are each independently an integer of 0 or 1; q is an integer of 0 to 7; and r is an integer of 0 or 1. |
