发明名称 |
DDS COMPOUNDS AND METHOD FOR ASSAYING THE SAME |
摘要 |
<p>A DDS compound comprising a carboxy(C1-4)alkyldextran polyalcohol modified with a saccharide compound and a residue of drug compound bound to the carboxy(C1-4)alkyldextran polyalcohol, and a method for measuring a DDS compound in which a polymer carrier and a residue of drug compound are bound to each other by means of a spacer comprising 2 to 8 amino acids linked by peptide bond(s), which comprises the steps of treating the DDS compound with a peptidase, and measuring the resulting hydrolysate.</p> |
申请公布号 |
EP1155702(A1) |
申请公布日期 |
2001.11.21 |
申请号 |
EP19990952805 |
申请日期 |
1999.10.29 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
SUSAKI, HIROSHI;INOUE, KAZUHIRO;KUGA, HIROSHI;IKEDA, MASAHIRO;SHIOSE, YOSHINOBU;KORENAGA, HIROSHI |
分类号 |
A61K31/4745;A61K47/48;C08B37/02;(IPC1-7):C08B37/02;C08B37/00;C07D491/22;A61K31/474 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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