| 摘要 |
<p>The present invention is composed of an amide derivative represented by the following formula Ä1Ü or pharmaceutically acceptable salt thereof: <CHEM> wherein R<1> and R<2> may be the same or different and each is hydrogen, alkyl which may be substituted, acyl, aryl which may be substituted, or an aromatic heterocyclic group which may be substituted; R<3>, R<4>, R<5>, and R<6> may be the same or different and each is hydrogen, halogen, hydroxy, amino which may be substituted, alkyl which may be substituted, alkoxy, or nitro and the like; and R<7> represents cyclic amino which may be substituted or azabicycloalkylamino which may be substituted, and a pharmaceutical composition which comprises it as an active ingredient. The compound of the invention is useful as an inhibitor of TGF- beta production or an antagonist of TGF- beta .</p> |
