发明名称 |
Reagent for the diagnosis of rheumatoid arthritis |
摘要 |
<p>A gene encoding a novel membrane protein polypeptide having pre-B cell growth-supporting ability, and a novel membrane protein polypeptide consisting of 180 amino acid residues having pre-B cell growth-supporting ability or a part of it. A method for producing said novel membrane protein polypeptide by preparing transformants by transforming a host cell with a vector containing said gene and culturing said transformants. A monoclonal antibody recognizing said novel membrane protein polypeptide. The above gene encodes the membrane protein having pre-B cell growth-supporting ability. The homogeneous and purified novel membrane protein polypeptide can be produced in large quantities and in addition, monoclonal antibodies recognizing said polypeptide can be produced; thus it becomes possible to identify rheumatoid arthritis (RA) and also prepare reagents for the clinical diagnosis thereof. <IMAGE></p> |
申请公布号 |
EP1156061(A1) |
申请公布日期 |
2001.11.21 |
申请号 |
EP20010119504 |
申请日期 |
1994.10.14 |
申请人 |
HIRANO, TOSHIO |
发明人 |
HIRANO, TOSHIO;KAISHO, TSUNEYASU |
分类号 |
A61K39/00;C07K14/52;C07K14/705;C12N15/12;C12N15/19;C12P21/08;(IPC1-7):C07K16/18 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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