发明名称 |
Immunomodulatory human MHC class II antigen-binding peptides/proteins |
摘要 |
The present invention relates to human peptides/proteins comprising at least one antibody-based antigen-binding domain of human composition with a binding specificity for a human MHC class II antigen, wherein binding of said peptide/protein to said antigen expressed on the surface of a cell causes or leads to modulation of the immune system. The invention further relates to nucleic acids encoding said peptides/proteins, methods for production, immunosuppression, pharmaceutical and diagnostic compositions or kits comprising the peptides/proteins and uses of the peptides/proteins. |
申请公布号 |
EP1156062(A1) |
申请公布日期 |
2001.11.21 |
申请号 |
EP20000110063 |
申请日期 |
2000.05.12 |
申请人 |
GPC BIOTECH AG;MORPHOSYS AG |
发明人 |
ZOLTAN, NAGY;THOMASSEN-WOLF, ELISABETH;TESAR, MICHAEL |
分类号 |
G01N33/50;A61K38/00;A61K39/00;A61K39/395;A61K48/00;A61P1/00;A61P1/16;A61P1/18;A61P3/10;A61P13/12;A61P17/06;A61P19/02;A61P21/04;A61P25/02;A61P29/00;A61P37/02;A61P37/06;A61P43/00;C07K16/28;C12N1/15;C12N1/19;C12N5/06;C12N5/10;C12N15/09;C12P21/02;C12Q1/02;G01N33/53 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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