NOVEL SUBSTITUTED 1,2,4-TRIOXANES AS ANTIMALARIAL AGENTS AND A PROCESS OF PRODUCING THE SUBSTITUTED 1,2,4-TRIOXANES

摘要

The present invention relates to novel substituted 1,2,4-trioxanes that are useful as anti-malarial agents, and have a general formula 1,wherein R1 and R2 are selected from the group consisting of a hydrogen, a C1-11 alkyl group; R3 and R4 are selected from the group consisting of a hydrogen, a C1-11 alkyl group, a C3-10 aryl group, a C1-2CO2H carboxyalkyl group; and X represents hydrogen or a lower alkoxy group having 1 to 6 carbons.