Hyaluronidase activity and allergenic cell activity inhibitor

摘要

Disclosed is a novel hyaluronidase activity and allergenic cell activity inhibitive substance useful as an effective ingredient in an anti-inflammatory or antiallergic medicament, which is an ethyl alcohol extract from body tissues or mycelia tissues of a fungus Agaricus blazei. The desired inhibitive activity of the ethyl alcohol extract is significantly higher than the corresponding hot water extract of the same fungous tissues. This difference is very prominent when the Agaricus blazei fungus cultured in a culture medium containing wheat bran and pinewood chips in combination is used as the starting material of the ethyl alcohol extraction.