Immunosuppressive compositions

摘要

The invention features a composition containing an immunophilin-binding compound and a ginkgolide compound, methods of inducing immunosuppression, and methods of screening for immunosuppressive ginkgolide compounds. The ginkgolide compound is selected from the group consisting of a phosphodiesterase inhibitor, a platelet activating factor (PAFR) antagonist, and a free radical scavenger.