发明名称 |
Mast cell regulation |
摘要 |
A method of treatment of mast cell mediated inflammatory disorders in mammals comprising regulating the longevity and activity of activated mast cells by inhibiting the expression and/or function of the anti-apoptotic A-1/bfl-1 gene or gene product. The invention also provides the development and use of a compound capable of inhibiting the expression and/or function of the anti-apoptotic A-1/bfl-1 gene or gene product for the manufacture of a medicament for treating mast cell mediated inflammation in human tissues by regulating the longevity and activity of activated mast cells. |
申请公布号 |
AU5691401(A) |
申请公布日期 |
2001.11.20 |
申请号 |
AU20010056914 |
申请日期 |
2001.05.08 |
申请人 |
INNOVENTUS, UPPSALA LIFE SCIENCE AB |
发明人 |
GUNNAR NILSSON;ZOU XIANG |
分类号 |
G01N33/50;A61K31/366;A61K31/573;A61K31/7088;A61K38/00;A61K38/13;A61K45/00;A61P1/00;A61P11/02;A61P11/06;A61P17/00;A61P29/00;A61P37/08;A61P43/00;C12N15/12;C12Q1/02;C12Q1/68;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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