Compositions and methods for treatment of proliferative disorders

摘要

The present invention relates to compositions and methods for preventing and treating AIDS, AIDS-malignancy, and other tumors. In particular, this invention comprises modulation of mitogenic and angiogenic growth factors with lysyl oxidase and its homologues. In other aspects of this invention, lysyl oxidase and its homologues provide angiogenic inhibition to the transactivating protein Tat of HIV-1.