发明名称 |
Acid salts of cholesterol |
摘要 |
A stable aqueous dispersion which comprises a cationic lipid which is a molecule which comprises a cholesterol-derived lipophilic group, a linker bond which is hydrolyzable by cellular enzymes and relatively resistant to base-catalyzed hydrolysis, a spacer arm and a cationic amino group, and an appropriate co-lipid. The invention also includes the cationic lipids and mammalian plasmid DNA or other cells in admixture with the aqueous dispersion.
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申请公布号 |
US6319516(B1) |
申请公布日期 |
2001.11.20 |
申请号 |
US19990334313 |
申请日期 |
1999.06.16 |
申请人 |
THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION;MCMASTER UNIVERSITY |
发明人 |
HUANG LEAF;EPAND RICHARD M.;BOTTEGA REMO |
分类号 |
A61K9/127;A61K47/48;C07J9/00;C07J41/00;C12N15/64;C12N15/88;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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