发明名称 |
Sulfonyl aryl or heteroaryl hydroxamic acid compounds |
摘要 |
A sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity. A contemplated compound corresponds in structure to the formula wherein W and the R groups are defined elsewhere. |
申请公布号 |
AU5958901(A) |
申请公布日期 |
2001.11.20 |
申请号 |
AU20010059589 |
申请日期 |
2001.05.07 |
申请人 |
PHARMACIA CORPORATION |
发明人 |
LOUIS J. BEDELL;JOSEPH MCDONALD;THOMAS E BARTA;DANIEL P BECKER;SHASHIDHAR N RAO;JOHN N FRESKOS;BRENT V. MISCHKE;DANIEL P. GETMAN;GARY A DECRESCENZO;CLARA I VILLAMIL |
分类号 |
C07C311/16;C07C311/21;C07C317/44;C07D207/48;C07D211/96;C07D295/26 |
主分类号 |
C07C311/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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