发明名称 |
THERAPEUTIC METHOD AND COMPOSITION UTILIZING ANTIGEN-ANTIBODY COMPLEXATION AND PRESENTATION BY DENDRITIC CELLS |
摘要 |
Disclosed are methods and compositions for use in immunotherapy. These methods and compositions are particularly useful for exploiting dendritic cells to present an antigen to a patient, particularly where the patient has a disease associated with the antigen. The invention provides methods for treating a patient having a disease associated with an antigen. The methods according to the invention comprise combining <i>ex vivo</i> an antigen and an antigen-presenting cell binding agent specific for the antigen, and administering the composition to a patient suffering from a disease associated with the antigen, wherein the patient receives a therapeutic benefit. |
申请公布号 |
WO0185204(A2) |
申请公布日期 |
2001.11.15 |
申请号 |
WO2001IB01331 |
申请日期 |
2001.05.11 |
申请人 |
ALTAREX CORP. |
发明人 |
SCHULTES, BIRGIT;NOUJAIM, ANTOINE |
分类号 |
A61K45/00;A61K35/12;A61K39/00;A61K39/39;A61K39/395;A61P1/00;A61P1/18;A61P11/00;A61P13/08;A61P15/00;A61P25/28;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P31/20;A61P31/22;A61P33/00;A61P35/00;A61P37/00;A61P37/04;A61P43/00;C07K16/18;C07K16/28;C12P21/08 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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