发明名称 MALONANILIC ACID DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND USE THEREOF
摘要 <p>Compounds represented by the general formula (I) or pharmacologically acceptable salts thereof which have excellent effects of lowering neutral fat level and non-HDL cholesterol level in the blood, inhibiting or suppressing the accumulation of neutral fat in the liver and protecting or ameliorating the liver function and, therefore, are useful as preventives or remedies for circulatory diseases such as hyperlipemia, arteriosclerosis, fatty liver and hepatitis. In said formula, wherein W represents oxygen, sulfur, methylene, etc.; R represents hydrogen, C1-6 alkyl or arylalkyl; R?1 and R2¿ represent each alkyl, halogeno, etc.; R3 represents hydrogen, alkyl, halogeno, etc.; Y represents alkyl, -Q-T (wherein Q represents oxygen, methylene, hydroxymethylene, etc.; and T represents optionally substituted aryl, etc.); and Z represents hydrogen, alkoxy, etc.</p>
申请公布号 WO2001085670(P1) 申请公布日期 2001.11.15
申请号 JP2001003499 申请日期 2001.04.24
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