TRANSGENIC ANIMAL MODEL BY MINERALOCORTICOID RECEPTOR ANTISENSE EXPRESSION
摘要
The invention concerns a nucleic acid construct blocking the expression of the murine mineralocorticoid receptor, in particular a vector containing an RNA antisense, and a non-human transgenic animal in whose genome said construct is incorporated, said animal being useful in particular as model for studying pathologies wherein the mineralocorticoid is involved.
申请公布号
WO0185939(A1)
申请公布日期
2001.11.15
申请号
WO2001FR01400
申请日期
2001.05.09
申请人
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);JAISSER, FREDERIC;BEGGAHT, AHMED;FARMAN, NICOLETTE;PUTTINI, STEFANIA