发明名称 |
DRUG DELIVERY DEVICE, ESPECIALLY FOR THE DELIVERY OF LEVONORGESTREL |
摘要 |
The invention relates to a delivery device for the controlled release of the therapeutically active agent levonorgestrel, over a prolonged period of time, at a release rate of 0,1-200 mu g/day, said device comprising a core comprising at least said therapeutically active agent, and a membrane encasing said core wherein said membrane is made of an elastomer. According to the invention, the elastomer is a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si-atoms of the siloxane units, and the release rate of said therapeutically active agent of said delivery device is regulated by the amount of said 3,3,3-trifluoropropyl groups.
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申请公布号 |
WO0185132(A1) |
申请公布日期 |
2001.11.15 |
申请号 |
WO2001FI00406 |
申请日期 |
2001.04.27 |
申请人 |
LEIRAS OY;MARKKULA, TOMMI;ALA-SORVARI, JUHA;JUKARAINEN, HARRI;LEHTINEN, MATTI;RUOHONEN, JARKKO |
发明人 |
MARKKULA, TOMMI;ALA-SORVARI, JUHA;JUKARAINEN, HARRI;LEHTINEN, MATTI;RUOHONEN, JARKKO |
分类号 |
A61K9/00;A61K31/569;(IPC1-7):A61K9/00;A61M31/00 |
主分类号 |
A61K9/00 |
代理机构 |
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