| 发明名称 |
Immunoconjugates II |
| 摘要 |
<p>The invention relates to new immunoconjugates comprising of a monoclonal antibody or a fragment thereof specific for the human EGF-receptor molecule and a member of the chemokine family, preferably selected from the C-X-C family, e.g. Interleukin-8 (IL-8). The immunoconjugates induce cytotoxic and chemotactic activity and are suitable for a targeted tumor therapy.</p> |
| 申请公布号 |
EP0706799(B1) |
申请公布日期 |
2001.11.14 |
| 申请号 |
EP19950113956 |
申请日期 |
1995.09.06 |
| 申请人 |
MERCK PATENT GMBH |
发明人 |
HOELZER, WOLFGANG;MATZKU, SIEGFRIED, DR.;VON HOEGEN, ILKA, DR.;STRITTMATTER, WOLFGANG, DR. |
| 分类号 |
C12N15/02;A61K38/00;A61K38/19;A61K39/385;A61K39/395;A61K39/44;A61K47/48;A61P35/00;A61P43/00;C07K14/485;C07K14/52;C07K14/54;C07K14/705;C07K14/715;C07K16/00;C07K16/28;C07K16/46;C12N15/62;C12P21/08;C12R1/91;(IPC1-7):A61K47/48;C07K19/00 |
主分类号 |
C12N15/02 |
| 代理机构 |
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